Paul outlines his conversion experience and his calling from Jesus himself. This is to demonstrate his authority to preach the gospel. He explains his visit to the Apostles in Jerusalem and how they supported him in his ministry to the Gentiles.

Following a disagreement between Paul and Barnabas, they separated and Paul took Silas on his journey. The Holy Spirit hinders his progress in Bithynia and Paul has a vision of a man from Macedonia calling him to go there - to Europe.

From Cyprus, Paul and Barnabas went to Pisidian Antioch to the synagogue where Paul was invited to preach. He started with the Jewish scriptures and went on to explain that Jesus fulfilled the Messianic promises. Gentiles were also present. There was a division amongst the Jews but a church was established.

The leaders of the church in Antioch send out Barnabas and Paul on a mission to the Gentiles. They go to Cyprus first and preach. The proconsul believes but there is spiritual opposition from Elymas the sorcerer. A miracle occurs.

As the Jewish believers travelled further, following the persecution, they found Jews to spread the gospel but they also began to speak to non-Jews. The church in Antioch spontaneously grew and the need for leadership was noted by the Jerusalem church. They sent Barnabas and he sent for Paul to join him.